How does a (Developing) Nation dive deep quick into Research


How does a (Developing) Nation dive deep quick into Research

  • Scientific education video Websites
  • Mini-booklets, how-to books, magazines created by community, participants
  • Workshops
  • New format for Research publication:
    • Research Article: 2-3 pages; contains new scientific or engineering knowledge; New journals for publishing “research articles”
  • Partnership among expert researchers and individuals
  • Research equipment
  • Research Institutes; Academia – Industry – Government research laboratory partnership; Private research

Guidelines For Research In Neuroscience

Area Of Expertise: # Computational Neuroscience #NeuroEngineering  # Neuroscience

Guidelines For Research In Neuroscience:

Simulation is not enough (Specific cases),

Start building Models & Theories.

  • Trying to understand the brain by creating exact models of the brain with enormous computing power (costing Billions of dollars) is not going to work – as is intended. 
    • We are never going to understand how the brain works completely with data only from the lowest level (molecules, channels, neurons) with so much complexity involved.
    • There is so much genetic variation from mouse to mouse, primate to primate, that you can’t draw general conclusions from data of genetic expression of a single mouse. What happens in the brain data scanning initiatives is that data is gathered from a single organism. And what is required is something similar to functional genomics – sort of functional neuroscience – trying to understand the relation between behavior and what happens in the brain – not just cataloging what data from a particular brain looks like.
    • What we need is new models, new theories – that can explain all these data.
    • We don’t need to simulate large parts of the brain on computers. Our goal should be simulation of small parts and theoretical models that can explain data from those small parts of the brain. 
  • We need to start building models, theories. And then on top our first attempts at building models and theories, we will start building more accurate models.
    • Different structural levels found in the brain:
      • Molecules, Receptors, Neurotransmitters. 
      • Neuron, Channels, Synapse, Glial Cells.
      • Collection of neurons
      • Brain regions (e.g., Primary Visual Cortex)
      • Brain – Behavior;  
  • The new breed of Neuroscientists, with the aim of building models, theories of the brain, would try to learn how scientists with different backgrounds are studying Neuroscience.     
    • What diseases are Neurologists seeing in patients? How do the Neurologists explain them in terms of lesions, etc. in a particular brain region
    • Examples:
      • Speech – Broca’s area [2].
      • Synesthesia [3] – Cross-connections among nearby brain regions.
    • What diseases are Psychiatrists seeing in patients? How do they explain them in terms of excess or reduction in neurotransmitters? 
      • Examples: 
        • Schizophrenia – Excess of Dopamine [4]. 
    • Data from neurons, channels, molecules.
    • Data from specific brain regions (e.g., MRI, fMRI data).
    • Data from optogenetics – switching neurons on and off with light. 
    • Systems Neuroscience
    • Computer Models of brain. Connectomics.
    • What are we learning from our research in Artificial Intelligence about the requirements of intelligence? 
    • Cognitive Neuroscience – latest research on higher mental functions and brain. 
  • Psychologists have built models. Researchers interested in both Artificial Intelligence and Neuroscience have built models. Why not start by trying to explain those models with our understanding of the brain?

Large Neuroscience Projects


Vision Of Collaborative Research Platform

With the proliferation of global collaboration platform the World Wide Web, we need to direct research in the right direction – one that centers on solving real problems collaboratively, not just publication of random research papers (for getting promoted!).

A collaborative research platform could define substantial problems, each of them, if solved, can bring about revolutions, and break the substantial problems into manageable pieces, i.e., sub-problems and the sub-problems into even more manageable pieces, i.e., sub-sub-problems. Individual researchers or research groups could pick and work on manageable problems that match their abilities and interests and publish and share results on the platform. Researchers could define new problems, define new sub-problems, suggest improvements and changes on the platform.

A research paper could be co-authored by hundreds or even thousands of researchers scattered throughout the world.

For example, a high level problem could be “Codify Biology to the point that you can control biological processes and organisms”. The problem should have measurable, quantifiable goals. This high level problem could be divided into more manageable pieces and then into even more manageable pieces until they are solvable by individual researchers or research groups.

This would help the entire scientific community move forward towards practical goals much more rapidly.

What Google Could Focus On Next

Research Problems

  • Cracking Artificial Intelligence with great internal teams & external collaboration – new products, increasingly better existing products – essentially changes the world.
  • It was search, rules, first order logic, probability and other representations. Now, it’s all about learning from massive datasets. Revolutions are coming! Ultimate search engine!
  • Intelligent Personal Agent
  • Solving big problems (or as Google calls them “moon shots“) with (problem focused collaborative research) great internal teams & external collaboration / massive collaboration / open innovation
  • Solve for X, Google X
  • Application of Big Data: understanding complex systems better: finding answers to age old questions: Sociology, Behavioral Science, Political Science, Economics & Business
  • Exploration of new computing architectures – continuation of Moore’s law: exponential increase in processing power – computational power for data processing, intelligence.
  • Parallel computing architectures (e.g., GPUs); Molecular computing; Optical Computing; Quantum computing; Cognitive computing / Neuromorphic computing.
  • Brain-computer Interfacing
  • Google in our brain!
  • Integrating data from all the sources => Knowledge Mining, New Applications

People focused Social Problems

  • Education & Learning platform
    • Google Play for Education, ChromeBook. Singularity University. Technology and Education are great equalizers.
  • Platforms that empower people – the enormous potential in each and everyone of us is materialized
  • Wikinomics platform 
    • Global collaboration
    • Android, Play, Chrome
  • Products that take on social problems and scale using profit to reach millions
  • Funding / Growing / Working with entrepreneurs to solve problems people face.
  • Solving local, social and global problems (clean water, cheap energy etc.) utilizing massive collaboration and exponential technologies
    • Google Ideas. For-profit.

Healthcare & Biomedicine

  • Computational Biology / Bioinformatics, Systems Biology, Biology Engineering
  • Healthcare Informatics
  • Lifespan extension; Curing Diseases; Preventive Medicine; Personalized Medicine

Physical Digital Integration

  • Robotics, Automation
  • Car 2.0
  • Electric / hybrid Car? App Market Integration; Automation; Advanced Collision avoidance system
  • Ultimate goal: Self Driving Car, Intelligent Transportation System
  • Computational Materials Design
  • Internet of things; Smart cities; Smart Home; Sensor Web; Big data


Google bought 8 robotics companies in past 6 months.

Google started with Search; currently focusing more on platforms and services. Lately, excited about the prospects about Physical Digital Integration?

(Developers Users, Apps).
Next: Developers developing tools, components Users developing apps?


  • Android
  • Google Play (Streaming services?)
  • Chrome
  • Google App Engine
  • Google+
  • Google TV
  • (New) Google glass, Motorola, ChromeOS, ChromeBook



  • Maps
  • GMail
  • Youtube
  • Google Books





Fundamental Shift In Education: A Requirement Of Our Time

Fundamental shift in education is a requirement of our time.Searchable facts are available online. When you have the Internet at your fingertips aided by Google you can learn anything ever known to mankind.

Computational devices / apps {e.g., WolframAlpha} are available. We don’t need to do multiplications or divisions or even algebraic calculations anymore. Computer based Numerical Computing and Symbolic Algebra Systems (SageMathematicaMatlab) and Statistical Computing Systems (R) are available. All we need to learn is to turn real world problems into computer programs that can solve our problems.


Exponential growth of human knowledge means that much of what you know today would become obsolete ten years from now. So lifelong education is the norm.  

Breadth of knowledge will become increasingly important. You need to know what you need to know and once you know what you need to know, you can find it online.

Boundaries between different fields of study are opening up. We organized different fields of study (Physics, Chemistry, Biology etc.) more than hundred years ago. We organized everything related to life under Biology. The study of atoms and molecules and reactions was named Chemistry. Physics concerned itself with forces and matter of the universe and their interactions with the ultimate goal of reducing all forms of interaction into few fundamental laws (one law – “The Theory Of Everything” or so the Physicists say – if you are a bit ambitious!). But now in the light of new knowledge and better tools, new organization of fields of study is required.

As we gained knowledge about the chemical processes of life, we organized our knowledge under the name Biochemistry. Fields that used to be completely separate are merging in the light of new knowledge and better tools to tackle common problems. For example, Biology and Computer Science, once separated, have combined to form Computational Biology / Bioinformatics as a result of explosion both in genomic and more generally biological data and computational power. New fields of study like Bioengineering, Biophysics, Cognitive Neuroscience, Computational Materials Science have popped up. As we look forward into the future, we can see Computer Science and Physics combining to form Physical Digital Integration and creating a world that is much different and better than ours. 

The Education of future Engineers would be based on Science and Mathematics: learning a few concepts that can explain all the different tools, technologies, possibilities and limits.

With the proliferation of global collaboration platform The World Wide Web, we need to direct research in the right direction – one that centers on solving real problems collaboratively, not just publication of random research papers (for getting promoted!).

In short, a complete reorganization of Education as it is today. Are we ready?


Research Problems I Want To Work On

  1. How do you create Advanced Artificial Intelligence that is better than human experts and understands and can reason about everything on the Web and in the real world?
  2. How do you Codify Biology (DNA, Proteins, Metabolic and Signalling Pathways, Cells, Tissues, Organs, Body) so that you can predict and control? (Codification of Biology, Engineering Biology, Systems Biology, Computational Biology, Curing Diseases & Disabilities, Increasing Lifespans.) 
  3. How do you invent better tools, technologies (Imaging, Optogenetics) and Models for Understanding and Engineering the BrainHow do you Cure Neurological and Psychiatric Disorders?
  4. How do you Understand Complex Systems consisting of lots of interacting agents? (Application of Big Data; Inventing better Models, Mathematics, Algorithms to understand complex systems better; finding answers to age old questions in Sociology, Behavioral Science, Political Science, Economics & Business)
  5. How do you Design Materials and Nanostructures with required properties using Computers?
  6. How do you make Software Developers say 100 times more productive?
  7. How do you design an Effective Education and Learning and Research Platform?
  8. How do you create Platforms that empower people – so that the enormous potential in each and everyone of us is materialized?
  9. How do you take Human – Computer (networked) collaboration, intelligence to the next level?
  10. How do you integrate the Information World and the Physical World? (A world where the Physical world is completely aware of everything utilizing information from the Information World; the world of information is embedded in the Physical World.)
  11. How do you design Next Generation Manufacturing Technologies? (Fab-lab, 3D Printing, Automation)
  12. Exploration of new computing architectures – continuation of Moore’s law: exponential increase in processing power; computational power for data processing, intelligence; (Parallel computing architectures (e.g., GPUs); Molecular computing; Quantum computing; Cognitive computing / Neuromorphic computing)
  13. How do you solve Local, Social and Global problems (clean water, cheap energy etc.) utilizing massive collaboration and exponential technologies?
  14. How do you predict and prevent Natural Disasters?
  15. Joining the pieces of puzzle together to get a complete picture of the Ultimate Reality